As a hospital pharmacist, you can help colleagues determine the best way to estimate kidney function and adjust medications. Dosing based on estimated glomerular filtration rate (eGFR) is in labeling for more medications (meropenem/vaborbactam, baricitinib, etc). But CrCl and eGFR are NOT interchangeable, despite some guidance suggesting they are. Using eGFR when …
قراءة المزيدThink with me ㅡ The physician is about to prescribe rivaroxaban ( Xarelto ) to someone with atrial fibrillation (AF). Their eGFR is 45. The recommended dose in AF is 20 mg once daily, but the dose should be reduced to 15 mg once daily if creatinine clearance is 15–49 mL/min. Should physician prescribe 15 or 20 mg? You decide you had better calculate the patient’s c…
قراءة المزيدThe debate continues about whether to use creatinine clearance (CrCl) or estimated glomerular filtration rate (eGFR) for renal dosing. We used to just use the Cockcroft-Gault equation to calculate CrCl for renal dosing. But there's an increase in using eGFR calculated by the Modification of Diet in Renal Disease (MDRD) equation , such as in dosing recommen…
قراءة المزيدNPS | Notes in Pharmacy Specialties is a free, open-access, peer-reviewed site focused on pharmacy practice. Articles are immediately accessible, covering clinical pharmacy, pharmaceutical care, health promotion, informatics, and more.
Egypt - Phone: (+20)1210274589
Gmail: abdelwahabward@gmail.com
Social Plugin