Procalcitonin
Reevaluate protocols for ACUTE pancreatitis
As a clinical pharmacist, you must be kept up to date. New evidence will lead to questions about treating acute pancreatitis .. Fluids. The standard has been to give aggressive fluids in the first 24 hours. But this is based on limited evidence linking early hydration to lower mortality. Now stronger data show that aggressive f…
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Vonoprazan
Limit use of Voquezna for H. pylori
As a community pharmacist, you should be updated. Voquezna Dual Pak and Triple Pak will be new prescribed combos for treating H. pylori . These combos contain vonoprazan, the first potassium-competitive acid blocker (PCAB)... Think of vonoprazan as a "fancy PPI ", with some differences. For instance, PPIs block activ…
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GIT Infection
Medications for TRAVELER's diarrhea
As a pharmacy doctor, people often ask you, what to use for traveler's diarrhea. Travelers' diarrhea refers to diarrhea that develops in individuals from resource-rich settings during or within 10 days of returning from travel to resource-limited countries or regions. And these some medications used for managing traveler's diarrhea... …
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Infectious Diseases
Empiric antibiotics for intra-abdominal infections
Complicated intra-abdominal infections are problems in clinical practice and consume substantial hospital resources. New guidelines will clarify appropriate antibiotics for empiric treatment of complicated intra-abdominal infections ... Community-acquired infections For appendicitis and other mild to moderate community infections use a single age…
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Probiotics
Give probiotic at least 2 hours after antibiotic
More controversy is stirring up about using probiotics in the hospital. Some clinicians advocate using probiotics to help prevent antibiotic-associated diarrhea . For example, giving 12 patients a probiotic seems to prevent one case of antibiotic-associated diarrhea, and giving a probiotic to 29 patients seems to PREVENT one case of C. difficile -associated diarrhea …
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GIT Infection
Zofran for PEDIATRIC gastroenteritis
ACUTE GASTROENTERITIS IS DEFINED AS a diarrheal disease of rapid onset, with or without nausea, vomiting, fever, or abdominal pain. Pediatric acute gastroenteritis has always been a major cause of emergency department (ED) visits and hospitalizations. Pediatric complaints of vomiting and diarrhea have been on the rise, whether it be secondary to the new Omicron-varia…
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Probiotics
Continue to expect a limited role for probiotics
There are more questions about using probiotics ( Lacteol Forte ) in the hospital for GI disorders due to new American Gastroenterology Association guidelines . Continue to expect limited use. Evidence of benefit is generally weak and study results often conflict. Plus data from one species or strain can't be applied to another. Some clinicians…
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Vancomycin
First-line for clostridium difficile, vancomycin or fidaxomicin?
Debate will brew about FIRST-LINE medications for C. difficile based on differing recommendations in new guidelines. Oral metronidazole has fallen out of favour, because it's less effective than vancomycin. The American College of Gastroenterology now recommends either oral vancomycin or fidaxomicin for a first C. difficile episode. In contr…
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PPIs
Appropriate drug regimens for Helicobacter pylori eradication
Clarithromycin and tetracycline shortages will bring up more questions about appropriate drug regimens for H. pylori ( see Table 1 ) . Triple therapy with a proton pump inhibitor (PPI) , clarithromycin, and amoxicillin or metronidazole is often used first-line, but usually should NOT be. Efficacy rates are falling due to increasing clarithromycin resistance. For fu…
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