Pregnancy and Breastfeeding
Gastrointestinal agents during pregnancy and breastfeeding
FDA pregnancy categories prior to 2014, figure (1) . Gastroesophageal reflux disease (GERD) occurs in up to 80%, of pregnancies and peaks in the third trimester. The exact mechanism and pathogenesis of this condition associated with pregnancy is likely multifactorial ( table 1 ) . Figure (1) FDA pregnan…
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Pregnancy and Breastfeeding
OTC options for treating gastrointestinal issues in pregnancy
PREGNANT WOMEN WILL ASK THE PHARMACIST about OTCs for GI complaints. We know nausea and vomiting in pregnancy is common. But be ready to help manage other GI problems if nondrug measures aren't enough. HEARTBURN ― Suggest an antacid with calcium first or one with aluminum/magnesium ( Maalox , etc) . These are considered safe at labeled doses, work quickly an…
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Pregnancy and Breastfeeding
Dyspepsia and gastro-esophageal reflux during pregnancy
Overview ㅡ Dyspepsia is a term used to describe a number of symptoms associated with the upper gastrointestinal tract that may include upper abdominal pain or discomfort, a feeling of upper abdominal 'fullness' or 'heaviness', reflux, heartburn, belching, nausea, and vomiting... Causes. Dyspepsia in pregnancy is commonly due to gastro-esophage…
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Stress Ulcer
Management of gastroesophageal reflux disease
OVERVIEW ㅡ Gastroesophageal reflux disease (GERD) is a common chronic, relapsing condition that is associated with a risk of significant morbidity and the possibility of mortality from complications. Patients have heartburn, the hallmark of acid regurgitation, at least once a month. Many patients self-diagnose and self-treat, and do not seek medical attention for th…
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Stress Ulcer
Pharmacology of histamine 2 (H2) antagonists
Therapeutic actions ㅡ H2 antagonists or H2-blocker inhibit the action of histamine at the H2 receptors of the stomach, inhibiting gastric acid secretion and reducing total pepsin output; the resultant decrease in acid allows healing of ulcerated areas. See additional notes Peptic Ulcer; assessment and management and Dyspepsia . Th…
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