HIT
DOACs are options for treating HIT
As a hospital pharmacist, you will get questions about using direct oral anticoagulants (DOACs) for heparin-induced thrombocytopenia (HIT) . We usually treat HIT with IV argatroban or sometimes IV bivalirudin or subcutaneous fondaparinux ( Arixtra ). Then we transition to warfarin ( Marevan ) once the platelet count recovers, usually 150,000/mm3 or higher. Now there&…
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Thromboembolism
Weigh venous thromboembolism (VTE) prevention strategies in COVID-19
Clinicians are scrambling to optimize venous thromboembolism (VTE) prophylaxis for hospitalized patients with COVID-19. Data suggest these patients have a higher VTE risk than other hospitalized patients. Plus D-dimer and other markers are often elevated in COVID-19 especially in severe cases. But there’s little evidence about optimal VTE prophylaxis in patients wi…
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HIT
Heparin-induced thrombocytopenia (HIT)
DESCRIPTION ㅡ There are two types of heparin-induced thrombocytopenia (HIT)... Type 1: Isolated HIT develops early in heparin therapy and is benign. No resultant bleeding or thrombotic complications. HIT type 1 NOT mediated by the immune system (passive heparin binding to platelets resulting in a modest shortening of the platelet life span). The platelet count rarel…
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