As a critical care pharmacist, questions are still popping up about seizure prophylaxis after a neurological injury, trauma, intracranial hemorrhage, etc. Who should get it? Continue to use seizure prophylaxis after a SEVERE traumatic brain injury (TBI); Glasgow Coma Scale 3 to 8. About 1 in 10 TBI patients have seizures…
قراءة المزيدNew evidence will renew debate about which medication to use for status epilepticus patients who DON’T respond to a benzodiazepine. Continue to first optimize the benzodiazepine dose, such as giving up to 8 mg of lorazepam (drug of choice; duration of action 12–24 hours). There are several recommended options to try next, but many hospitals use IV fosphenytoin …
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