UTI
Antibiotic options for UTI in pregnancy
As a pharmacist, pregnant women will ask you about antibiotic safety for urinary tract infections (UTIs) partly due to new media headlines. A recent CDC report highlights that nitrofurantoin or TMP/SMX accounts for over 40% of prescribtion to treat a UTI in the first trimester and cautions about birth defects with these antibiotics. But this doesn't mean these…
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Seizures
Weigh considerations for anticonvulsant in women of childbearing age
As a preofessional pharmacist, you will need to navigate risks when antiepileptics are started in women of childbearing age. Keep in mind, these medications are often used for migraine, mood disorders, fibromyalgia, etc, NOT only seizures. Weigh teratogenic risk . Generally, feel comfortable if lamotrigine ( Lamictal ) or levetira…
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SSRIs
SSRIs during pregnancy
Women will ask you whether they should stop taking SSRIs during pregnancy due to recent headlines about autism risk. They're hearing about a new study that suggests taking SSRIs in the second or third trimester is linked to a higher risk of autism. But this study has flaws and does not prove antidepressants CAUSE a…
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Statins
Statins may be okay to use in pregnant patients
You will hear controversy about whether statins are okay to use in pregnant patients. This is coming up because labelling for statins in the U.S. will no longer say they're contraindicated during pregnancy . Experts now say statin benefits may outweigh risks in the very small group of pregnant patients at very high CV risk. This includes pregnant patients with ho…
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Pregnancy and Breastfeeding
Gastrointestinal agents during pregnancy and breastfeeding
FDA pregnancy categories prior to 2014, figure (1) . Gastroesophageal reflux disease (GERD) occurs in up to 80%, of pregnancies and peaks in the third trimester. The exact mechanism and pathogenesis of this condition associated with pregnancy is likely multifactorial ( table 1 ) . Figure (1) FDA pregnan…
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Pregnancy and Breastfeeding
Antibiotics use in pregnancy
INTRODUCTION ㅡ During pregnancy, untreated sexually transmitted or urinary tract infections are associated with significant morbidity, including low birth weight, preterm birth, and spontaneous abortion. Antibiotic exposures during pregnancy have been associated with both short‐term (e.g., congenital abnormalities) and long‐term effects (e.g., changes in gut microbi…
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Pregnancy and Breastfeeding
Medication safety and drug exposure in pregnancy
Introduction ㅡ Although some medicines are considered safe during pregnancy, the effects of other medicines on your unborn baby are unknown. Certain medicines can be most harmful to a developing baby when taken during the first three months of pregnancy, often before a woman even knows she is pregnant. Pain …
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Pregnancy and Breastfeeding
Over-the-counter (OTC) medications in pregnancy
Overview ㅡ Over-the-counter (OTC) medications are pharmacologic agents that patients can buy without a physician’s prescription. They come in different forms, such as pills, creams, ointments, patches, or drops... Table (1) FDA pregnancy risk classification system. Diagnosis …
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