SNRIs
Cymbalta for lower back pain
Cymbalta (duloxetine) will be used more for chronic musculoskeletal pain in the lower back or due to osteoarthritis . Cymbalta is already approved for neuropathic pain . Plus, it's approved for chronic musculoskeletal pain, so physicians are hearing more about this use, too. Some antidepressants do have analgesic effects, especially tricyclics (amitriptyline, …
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Rheumatology
Drug interactions with colchicine
As a clinical pharmacist, you should focus on common and serious drug interactions. Dosing and drug interactions with colchicine for acute gout are still causing confusion. We're all used to the old way of dosing colchicine for acute gout, two tabs initially then one tab every 2 hours until the pain stops, diarrhea starts, or a max of 5 tabs per day. But this c…
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Rheumatology
Supplements for OSTEOarthritis
As a community pharmacist, you will get questions about supplements for osteoarthritis. Guidelines don’t recommend any oral supplements for most patients with osteoarthritis , due to limited evidence. But some people swear by them or want to give them a try, especially if topical or oral NSAIDs aren’t an option. Help sort through the ple…
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Rheumatology
The latest recommendations for treating osteoarthritis
As a clinical pharmacist, it's essential to emphasize that exercise (such as walking and strengthening exercises) and weight loss, if needed, remain the main approaches for management. It's important to note that while oral NSAIDs like naproxen are often effective, they may not be suitable for everyone due to potential risks to the heart, stomach, and kidney…
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Rheumatology
Screening and management of osteoporosis
Introduction ㅡ Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis itself is asymptomatic, and often remains undiagnosed until a fragility fracture occurs. An osteoporotic fracture is a fragility fracture occurring as a consequen…
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