As a clinical pharmacist, you will hear more controversy about how long patients should take bisphosphonates (alendronate, etc) for osteoporosis. Many patients get put on a bisphosphonate to prevent fractures and are left on them indefinitely. But long-term use may be associated with problems, jaw osteonecrosis and atypical femur fractures. …
قراءة المزيدAs a nutrition support pharmacist, people are asking you if they should take MORE vitamin D and LESS calcium. This follows some recommendations by many experts... According to Vitamin D , some experts recommend that adults get 1000 IU/day of vitamin D instead of just 400 IU/day. They say that vitamin D is MORE important than calcium for bone health and has o…
قراءة المزيدRECENT DATA WILL BRING MORE CLARITY ABOUT THE ROLE OF VITAMIN D SUPPLEMENTS IN ADULTS. The year 2019 wasn't good for the sunshine vitamin (vitamin D). That's because randomized trials showed that vitamin D supplements don't benefit heart disease, various types of cancer, or diabetes, despite years of promising observational data. Plus most evidence sugge…
قراءة المزيدHow to manage osteoporosis when patients don't get enough benefit from a bisphosphonate?! ― Reassess your treatment plan for patients who continue to have significant bone loss, or a fracture, despite being on a bisphosphonate. Continue the basics. Recommend weight-bearing exercise, adequate vitamin D and calcium , etc. Check adherence. Ab…
قراءة المزيدE ssential of diagnosis ― Fracture propensity of spine, hip, pelvis, and wrist from depletion of bone matrix with subsequent demineralization. Asymptomatic until a fracture has occurred. Serum PTH, calcium, phosphorus, and alkaline phosphatase usually normal and serum 25-hydroxyvitamin D levels often low as a comorbid condition. Most common causes of osteoporosis in…
قراءة المزيدIntroduction ㅡ Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis itself is asymptomatic, and often remains undiagnosed until a fragility fracture occurs. An osteoporotic fracture is a fragility fracture occurring as a consequen…
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