Rheumatology
Caffeine may worsen rheumatoid arthritis
As a clinical pharmacist, you should always be aware of drug interactions. There's concern that caffeine might reduce the efficacy of methotrexate for rheumatoid arthritis ... Methotrexate decreases inflammation by increasing adenosine levels. Caffeine might cause a problem, because it's an adenosine receptor ANTAGONIST. It's goi…
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Steroids
Help patients stick with METHOTREXATE for rheumatoid arthritis
New guidelines will lead to questions about treating rheumatoid arthritis , especially with the plethora of medication options. For more information, see topic on Overview of rheumatoid arthritis . Which medication is first-line ? Recommend sticking with oral methotrexate 7.5 mg once weekly for most patients. Generally ad…
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Steroids
Identifying patients at risk for fractures due to chronic steroids
As a clinical pharmacist, it is important to address the therapy gap in preventing osteoporosis and fractures among patients on chronic corticosteroids. More than one in 10 patients using these medications long-term will experience a fracture as a result of glucocorticoid-induced osteoporosis. It is crucial for you as a pharmacist to be vigilant in identifying patien…
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