UTI
Antibiotics for urinary tract infections in ELDERLY patients
As a clinical pharmacist, you will be asked more, which antibiotics should be recommended for urinary tract infections in elderly patients? It depends on whether it's a "complicated" UTI or not. We know all UTIs in older MEN are considered complicated due to possible prostate involvement. UTIs in women can also be complicated due to a catheter, obstr…
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UTI
Antibiotic options for UTI in pregnancy
As a pharmacist, pregnant women will ask you about antibiotic safety for urinary tract infections (UTIs) partly due to new media headlines. A recent CDC report highlights that nitrofurantoin or TMP/SMX accounts for over 40% of prescribtion to treat a UTI in the first trimester and cautions about birth defects with these antibiotics. But this doesn't mean these…
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UTI
Empiric antibiotics for pyelonephritis
As an infectious disease pharmacist, you will hear controversy over the best way to treat patients hospitalized with pyelonephritis . There's limited evidence to guide empiric antibiotic choices in these patients and growing concerns about resistance to commonly used antibiotics, such as quinolones. Use your antibiogram to choose an antibiotic with good empiric c…
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Trimethoprim
Think carefully before prescribing Septazole with potassium-boosting drugs
AS A PHARMACIST, you will hear more about possible harm when TMP/SMX ( Bactrim, Septrin, Septazole , etc) is combined with medications that increase potassium ( ACEIs , spironolactone , etc). This interaction is more risky than previously thought and is popping up on more drug interaction software . Trimethoprim decreases urinary excre…
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TMP/SMX
Trimethoprim/sulfamethoxazole (TMP/SMX) in combination with drugs that increase potassium
As a pharmacist, you should be be careful when use of trimethoprim/sulfamethoxazole ( Bactrim, Septrin, etc) in combination with drugs that increase potassium like angiotensin converting enzyme inhibitors (ACEI) , angiotensin receptor blockers (ARBs) or spironolactone. Remmember that trimethoprim/sulfamethoxazole labeling has a precaution about hyperkalemia, and …
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