Rheumatology
Recommend allopurinol instead of febuxostat for most chronic gout patients
AS A PHARMACIST, you'll hear about an advocacy group pushing for withdrawal of the gout med febuxostat ( Uloric, Xanthistop ) due to concerns it increases mortality. FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat), available at: https://www.fda.gov/drugs/drug-safety-and-availability/fda-adds-boxed-warning-increased-ri…
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Rheumatology
Allopurinol or febuxostat for chronic gout?
As a pharmacist, you’ll get questions about managing chronic gout due to continued debate over whether to aim for a target uric acid level. We know to consider a chronic medication to lower uric acid when gout causes problems such as tophi or 2 or more acute gout flares/year. But there’s not much evidence on the best way to titrate medications. Some “treat to target”…
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Rheumatology
Comparison of GOUT therapies
G out is one of the most common forms of arthritis. It occurs more often in men. During a gout attack, high uric acid levels lead to the formation of uric acid crystals in joints (usually knees, ankles, and feet; can affect elbows, wrists, and fingers). Symptoms can include pain, redness, joint swelling and limited range of motion, and fever. Gout risk factors inc…
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