Optimizing Meds
Optimizing meds in patients with HFrEF and CKD
Few patients with chronic kidney disease (CKD) are on optimized meds for heart failure with reduced ejection fraction (HFrEF) . It’s a delicate balance... Hyperkalemia can occur with an ACEI or ARB, Entresto (sacubitril/valsartan), or an aldosterone antagonist. Plus, these meds or SGLT2 inhibitors ( Forxiga, etc ) can cause an initial bump in serum creatinine…
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Sepsis
Update your SEPSIS protocols
As a critical care pharmacist, you will hear ongoing debate about MANAGING SEPSIS IN ADULTS. Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Update your protocols using the latest data... Fluids Verify your sepsis order set includes balanced fluids ( Lactated Ringer's, Plasma-Lyte, etc…
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Status Epilepticus
Assess the need for SEIZURE prophylaxis
As a critical care pharmacist, questions are still popping up about seizure prophylaxis after a neurological injury, trauma, intracranial hemorrhage, etc. Who should get it? Continue to use seizure prophylaxis after a SEVERE traumatic brain injury (TBI); Glasgow Coma Scale 3 to 8. About 1 in 10 TBI patients have seizures…
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Stroke
DAPT after an ischemic stroke or TIA?
New data will raise questions about optimal use of short-term dual antiplatelet therapy (DAPT) after an ischemic stroke or TIA. We know that short-term DAPT, such as aspirin plus clopidogrel for 21 days, reduces recurrent stroke risk compared to aspirin alone. But most evidence is with starting DAPT within 24 hours. And data are mostly for patients with a minor st…
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Oncology
Chemotherapy-induced Nausea & Vomiting: How to Defeat it?
OVERVIEW ― No one can deny that Chemotherapy-induced Nausea & Vomiting (CINV) is the most common undesired effect of chemotherapy and the most common cause of anxiety and distress in patients with cancer. Untreated CINV could affect 60% to 80% of cancer patients and impact their Quality of Life (QOL) as well as their families, which often leads them to discontinu…
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Locodo
Know COLCHICINE's role in chronic coronary disease
As a cardiovascular pharmacist, you’ll hear buzz about new Rx colchicine ( Lodoco ) for patients with chronic coronary disease. There’s been growing interest in using colchicine to reduce CV risk, due to its anti-inflammatory effect... 💊⚕️ Lodoco is the same drug we use for gout , but it’s 0.5 mg instead of 0.6 …
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